首页> 外国专利> A NOVEL HERBAL COMPOSITION OF AQUEOUS EXTRACT OF CAPPARIS DECIDUA AND ITS ANTINEPHROLITHIASIS ACTIVITY

A NOVEL HERBAL COMPOSITION OF AQUEOUS EXTRACT OF CAPPARIS DECIDUA AND ITS ANTINEPHROLITHIASIS ACTIVITY

机译:CAPCAPRIS DECIDUA水提物的新型草药组成及其抗精神分裂症的活性。

摘要

A kidney stone is like a small rock that forms in the kidney. Stones form when certain chemicals in the body clump together. A stone can either stay in the kidney or travel through the urinary system. Very small stones might pass through the urinary system without causing much pain. Larger stones can block the flow of urine if they get stuck in the ureters or urethra. Kidney stones do not usually cause any symptoms until they start to pass. The study was undertaken to investigate the anti nephrolithiasis activity of Capparis decidua. In preventive regimen AECD 800 mg/kg (57.35% relief) show greater Creatinine clearance then standard drug cystone (34.54% relief) and in curative regimen cystone (125.33% relief) has greater effect then AECD 800 mg/kg (42.48% relief). Test drug show dose dependent therapeutic efficacy. Therapeutic effect of test drug increase with increasing dose.
机译:肾结石就像在肾脏中形成的小石头。当体内某些化学物质聚集在一起时,就会形成石头。结石可以留在肾脏中,也可以穿过泌尿系统。很小的结石可能会通过泌尿系统而不会引起太大的疼痛。如果较大的结石卡在输尿管或尿道中,则会阻塞尿液的流动。肾结石通常在通过之前不会引起任何症状。进行了该研究以调查蜕皮Capparis的抗肾结石病活性。在预防性方案AECD 800 mg / kg(减轻57.35%)中,肌酐清除率高于标准药物cystone(减轻34.54%);在治疗性方案cystone(减轻125.33%)中效果优于AECD 800 mg / kg(减轻42.48%) 。测试药物显示剂量依赖性治疗功效。受试药物的治疗效果随着剂量的增加而增加。

著录项

  • 公开/公告号IN2014DE01565A

    专利类型

  • 公开/公告日2016-08-31

    原文格式PDF

  • 申请/专利权人

    申请/专利号IN1565/DEL/2014

  • 申请日2014-06-10

  • 分类号A61K9/68;

  • 国家 IN

  • 入库时间 2022-08-21 14:25:22

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