首页> 外国专利> Dexanabinol, or a pharmaceutically acceptable salt thereof, for the apoptosis of cancer other than melanoma and use thereof in the manufacture of a medicament for the apoptosis of cancer, other than melanoma and a pharmaceutical composition comprising the same

Dexanabinol, or a pharmaceutically acceptable salt thereof, for the apoptosis of cancer other than melanoma and use thereof in the manufacture of a medicament for the apoptosis of cancer, other than melanoma and a pharmaceutical composition comprising the same

机译:地塞那酚或其药学上可接受的盐,用于除黑色素瘤以外的癌症的细胞凋亡,及其在制备用于除黑色素瘤以外的癌症的细胞凋亡的药物中的用途以及包含该药物的药物组合物

摘要

There is described a therapeutic agent capable of directly or indirectly having an effect on the proteins N-methyl-D-aspartate (NMDA), Cyclooxygenase-2 (COX-2), Tumour Necrosis factor alpha (TNF-a), Nuclear factor-kappa B (NFKB), Cyclin-dependent kinases, e.g. CDK2/A and CDK5/p25, Histone acetyltransferase (HAT) and Farnesyltransferase, simultaneously, sequentially or separately. There is especially described dexanabinol, or a derivative thereof, as the therapeutic agent.
机译:描述了一种能够对蛋白质N-甲基-D-天冬氨酸(NMDA),环氧合酶2(COX-2),肿瘤坏死因子α(TNF-a),核因子-产生直接或间接影响的治疗剂。 κB(NFKB),细胞周期蛋白依赖性激酶,例如CDK2 / A和CDK5 / p25,组蛋白乙酰基转移酶(HAT)和法尼基转移酶同时,顺序或分开使用。特别地,描述了地塞那酚或其衍生物作为治疗剂。

著录项

  • 公开/公告号IL218008A

    专利类型

  • 公开/公告日2016-10-31

    原文格式PDF

  • 申请/专利权人 E-THERAPEUTICS PLC;

    申请/专利号IL20120218008

  • 发明设计人

    申请日2012-02-09

  • 分类号A61K;A61P;

  • 国家 IL

  • 入库时间 2022-08-21 14:26:04

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号