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ANTIMYCOTIC AND PREBIOTIC PHARMACEUTICAL COMPOSITION AND A METHOD FOR TREATING CANDIDAL VAGINITIS
ANTIMYCOTIC AND PREBIOTIC PHARMACEUTICAL COMPOSITION AND A METHOD FOR TREATING CANDIDAL VAGINITIS
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机译：抗菌和益生元的药物组合物和治疗念珠菌阴道炎的方法
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摘要
The invention relates to medicine and pharmacology, more particularly to a pharmaceutical composition in the form of vaginal suppositories for treating and preventing candidal vaginitis and vulvovaginitis, containing a mixture of at least one antimycotic from the group of polyene antibiotics or nitrofurans and prebiotic - lactulose with polymerization degree from 2 to 30, with the following concentration of the components weight/volume per composition mass: antimycotic from the group of polyene antibiotics or nitrofurans - 0.0001 to 5%, lactulose - 0.1 to 40.0%, excipients - the rest. The contents of the composition for therapeutic use make it possible to achieve the synergistic effect of stimulating the growth of the normal vaginal microflora through the presence of prebiotics and inhibiting the growth of and eliminating pathogenic Candida fungi through the presence of modern antimycotics. Furthermore, the composition substantially contains such antimycotics to which representatives of the normal flora, i.e. lactobacilli and bifidobacteria, are insensitive. Also claimed is a method for treating mycetogenous or bacterial vaginosis, vaginitis and vulvovaginitis, which is carried out with the aid of the antimycotics and prebiotics in a medicinal form for local application.
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