首页> 外国专利> METHODS FOR PRODUCING DOUBLE SALTS OF LORCASERIN (VARIANTS), PRODUCTS OF SAID METHODS, DOUBLE SALTS, PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND/OR PROPHYLAXIS OF OBESITY-RELATED DISORDERS, THE USE OF SAME, AND METHOD FOR THE TREATMENT AND/OR PROPHYLAXIS OF OBESITY-RELATED DISORDERS

METHODS FOR PRODUCING DOUBLE SALTS OF LORCASERIN (VARIANTS), PRODUCTS OF SAID METHODS, DOUBLE SALTS, PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND/OR PROPHYLAXIS OF OBESITY-RELATED DISORDERS, THE USE OF SAME, AND METHOD FOR THE TREATMENT AND/OR PROPHYLAXIS OF OBESITY-RELATED DISORDERS

机译：制备洛卡瑟林（各种）双盐的方法，上述方法的产品，双盐，与肥胖相关的疾病的治疗和/或预防的药物成分，使用方法及方法，和/或预防的方法相关疾病

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摘要

The invention relates to medicine, particularly to methods for producing double salts of (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1N-3-benzazepine (lorcaserin), products of the methods and compositions for the treatment and/or prevention of obesity comprising double salts of lorcaserin, phthalic acid and metformin or lorcaserin, phthalic acid and basic amino acid. The invention also relates to the use of the said pharmaceutical compositions for the treatment and/or prevention of disorders related to excess weight and/or obesity, including in the case of diabetes mellitus, and to methods for the prophylaxis or treatment of disorders related to excess weight and/or obesity, including in the case of diabetes mellitus.

机译：本发明涉及药物，尤其涉及（1R）-8-氯-1-甲基-2,3,4,5-四氢-1N-3-苯并ze庚因（氯卡色林）的复盐的制备方法，产品和用于治疗和/或预防肥胖的组合物，其包含氯酪蛋白，邻苯二甲酸和二甲双胍的复盐或氯酪蛋白，邻苯二甲酸和碱性氨基酸。本发明还涉及所述药物组合物在治疗和/或预防与超重和/或肥胖有关的疾病中的用途，包括在糖尿病的情况下，以及与所述疾病有关的预防或治疗方法。体重过重和/或肥胖，包括糖尿病。

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公开/公告号EA022748B1

专利类型
公开/公告日2016-02-29

原文格式PDF
申请/专利权人 DELCROSTON MANAGEMENT LIMITED;
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申请/专利号EA20140000536
发明设计人 BELY PETR ALEKSANDROVICH;CHERTORIZHSKIY EVGENIY ALEKSANDROVICH;BELOV EVGENIY YURIEVICH;
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申请日2014-06-02
分类号C07D223/16;A61K31/55;A61P3/04;
国家 EA
入库时间 2022-08-21 14:26:19

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