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Signaling peptide enterotoxin II of E. coli modified and a microorganism expressing a fusion protein of the peptide and a heterologous protein.
Signaling peptide enterotoxin II of E. coli modified and a microorganism expressing a fusion protein of the peptide and a heterologous protein.
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机译:修饰了大肠杆菌的信号肽肠毒素II,并表达了该肽和异源蛋白融合蛋白的微生物。
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摘要
"Beacon of E.coli enterotoxin II peptide modified and a microorganism expressing a fusion protein of the peptide and a heterologous protein. A heterologous protein is produced by: (I) the cultivation of a microorganism transformed with a vector comprising a gene coding a peptide expression marker of enterotoxin II B.Coli fused to heterologous protein modified to produce and secrete the heterologous protein to periplasma, the peptide marker of enterotoxin II b.coli modified is obtained by substitution of at least one of the second, fourth, fifth, tenth second, the twentieth and twenty sec... The amino acids of the signaling peptide enterotoxin II B.Coli in the following sequence of amino acid (SRQ ID: 1) with another amino acid, provided that at least one of the second and fourth amino acids, peptide modified is lysine; and (II) recovering the heterologous protein of periplasma.
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