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immunogenic molecule, composition, method of treating or preventing a condition caused or associated with plasmodium falciparum infection and screening for the presence of an antibody inhibiting plasmodium falciparum invasion in a patient; and, use of an immunogenic molecule and a composition
immunogenic molecule, composition, method of treating or preventing a condition caused or associated with plasmodium falciparum infection and screening for the presence of an antibody inhibiting plasmodium falciparum invasion in a patient; and, use of an immunogenic molecule and a composition
This invention relates to an immunogenic molecule comprising a contiguous amino acid sequence of an invasion ligand of a strain of Plasmodium falciparum, the invasion ligand capable of binding to an erythrocyte receptor, the receptor function being resistant to trypsin and neuraminidase and chymotrypsin, wherein when administered to a subject the molecule is capable of inducing an immune response to the strain. The invention further relates to compositions and methods for the treatment of diseases such as malaria.
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