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首页> 外国专利> The use of ethanolic extract and fractions flavonu00f3idicas of Thuja occidentalis as antifungal agents

The use of ethanolic extract and fractions flavonu00f3idicas of Thuja occidentalis as antifungal agents

机译：柏柏乙醇提取物和黄酮级分作为抗真菌剂的应用

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The use of ethanolic extract and fractions flavonu00f3idicas of Thuja occidentalis as antifungal agents. This patent relates to the use of the ethanolic extract and fractions flavonu00f3idicas of Thuja occidentalis as antifungal agents. The alcoholic extract of T. occidentalis has fluid activity against Candida krusei (CIM of 2.08 pg / ml quecertina - 3 - ramnosu00eddeo), C. glabrata, C.Parapsilosis and C. albicans (CIM of 8:32 pg / ml quecertina - 3 - ramnosu00eddeo). For the fraction flavonu00f3idica, constituted mostly by flavonoids myricetin - 3 - ramnosu00eddeo, quercetin - 3 - ramnosu00eddeo and kaempferol - 3 - ramnosu00eddeo; susceptibility testing showed fungicidal action against the isolated C. albicans (CIM 64 to 512 pg / ml), C. glabrata (CIM 128 pg / ml ), C.Krusei (rings 4 to 128 pg / ml) and C. parapsilosis (CIM 64 pg / ml). For the fraction flavonu00f3idica B constituted mostly by flavonoids amentoflavona and hinokiflavona, susceptibility testing showed fungicidal action against the isolates of C. albicans (cim2048 pg / ml), C. glabrata (CIM 512 pg / ml), C. krusei (CIM 256 to 512 pg / ml) and C. parapsilosis ( CIM 1024 pg / ml).Whereas the criteria suggested by holetz et al. (2002), the results showed that the ethanolic extract and fractions flavonu00f3idicas of T. occidentalis have good antifungal activity, therefore, have the potential to be used in the production of herbal medicines against infections caused by Candida albicans and promoting the reduction of Mo The RBI - mortality.
机译：西方柏柏的乙醇提取物和黄酮级分作为抗真菌剂的用途。该专利涉及西崖柏的乙醇提取物和黄酮级分作为抗真菌剂的用途。西方隐球菌的乙醇提取物对克鲁斯假丝酵母（CIM为2.08 pg / ml雀形目-3-ramnos u00eddeo），光滑隐孢子虫，假单胞菌和白色念珠菌（CIM为8:32 pg //）具有流体活性ml quecertina-3-ramnos u00eddeo）。对于级分黄酮，主要由类黄酮杨梅素-3-ramnos u00eddeo，槲皮素-3-ramnos u00eddeo和山emp酚-3-ramnos u00eddeo组成;药敏试验显示对分离的白色念珠菌（CIM 64至512 pg / ml），光滑念珠菌（CIM 128 pg / ml），克鲁氏梭菌（4至128 pg / ml环）和C.副瘫痪（CIM 64 pg / ml）。对于主要由类黄酮amentoflavona和hinokiflavona组成的部分flavon u00f3idica B，药敏测试显示对白色念珠菌（cim2048 pg / ml），光滑念珠菌（CIM 512 pg / ml），克鲁氏梭菌（C. krusei）的分离物具有杀真菌作用。 （CIM 256至512 pg / ml）和C. parapsilosis（CIM 1024 pg / ml）。 （2002年），结果表明，西方提取物和西方黄连的乙醇提取物和黄酮级分具有良好的抗真菌活性，因此，有潜力用于生产草药以抵抗由白色念珠菌引起的感染并促进减少白念珠菌的产生。莫打点-死亡率。

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