首页> 外国专利> methods for treating patient by separating ctcs, capturing circulating tumor cells (ctc) in body fluid and discovering drugs, isolated ctcs, body fluid ctc capture filter and extracorporeal devices for capturing ctcs in body fluid

methods for treating patient by separating ctcs, capturing circulating tumor cells (ctc) in body fluid and discovering drugs, isolated ctcs, body fluid ctc capture filter and extracorporeal devices for capturing ctcs in body fluid

机译：分离ctcs，捕获体液中的循环肿瘤细胞（ctc）并发现药物的治疗方法，分离的ctcs，体液ctc捕获过滤器和用于捕获体液中ctcs的体外装置

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摘要

methods for treating patient by separating ctcs, to capture circulating tumor cells (ctc) in body fluid and to discover drugs, isolated ctcs, body fluid ctc capture filter and extracorporeal devices for capturing ctcs in body fluid. Embodiments of the present disclosure are directed to the separation / capture of specific cells and / or contaminants, as well as the determination, monitoring and treatment of cancer. In addition, some embodiments are directed to methods, systems and devices for removing cancer cells, stem cells and / or tumor cells in vivo or in vitro from a body fluid to prevent or prevent the proliferation of a cancer. Some embodiments provide a blood-compatible filter comprising, for example, a membrane provided with a series of (preferably more accurate) apertures that produce minimal detrimental effect both quantitatively and qualitatively on cells present in the body fluid during the separation process. For example, in some embodiments, a higher percentage of circulating tumor cells are captured by a filter, while a higher percentage of leukocytes, for example, may pass, in which passing leukocytes retain their vitality.

机译：通过分离ctcs，捕获体液中的循环肿瘤细胞（ctc）并发现药物，分离的ctcs，体液ctc捕获过滤器和用于捕获体液中ctcs的体外装置的方法本公开的实施例针对特定细胞和/或污染物的分离/捕获，以及癌症的确定，监测和治疗。另外，一些实施方案涉及用于从体液体内或体外去除癌细胞，干细胞和/或肿瘤细胞以预防或预防癌症扩散的方法，系统和装置。一些实施方案提供了血液相容性过滤器，其包括例如膜，该膜具有一系列（优选更精确的）孔，所述孔在分离过程中对存在于体液中的细胞定量和定性地产生最小的有害作用。例如，在一些实施方案中，较高百分比的循环肿瘤细胞被过滤器捕获，而较高百分比的白细胞例如可以通过，其中经过的白细胞保持其活力。

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公开/公告号BR112012024350A2

专利类型
公开/公告日2016-05-24

原文格式PDF
申请/专利权人 VIATAR LLC;
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申请/专利号BR20121124350
发明设计人 CORNELIS JOHANNES MARIA VAN RIJN;ILAN REICH;JACOB BAGGERMAN;
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申请日2011-03-31
分类号A61M1/36;B01D67;B01D71/02;G01N33/49;G01N33/50;
国家 BR
入库时间 2022-08-21 14:27:25

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