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Modifiers of tastes, Flavors, flavor substances, Breeders of Taste, flavor substances and / or Enhancing Sweet or umami taste and Use thereof

机译：口味，风味剂，风味物质，风味育种者，风味物质和/或增强甜味或鲜味的改性剂及其用途

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摘要

This application relates to the discovery that certain amides are not of Natural Origin, non Peptide amide and amide Derivatives, such as oxalamidas, urea and acrylamides are useful Modifiers such as flavor or Taste, flavor or flavor Enhancers or FLAVORING agents and Taste,More in particular Modifiers of tasty Taste (umami Taste of monosodium glutamate) or sweet, Sweet or Savory FLAVORING agents or Enhancers of sweet or Savory Taste, Food, Beverage and other edible or medicinal products or compositions that are administered orally.Claim 1, characterized in that: an amide Compound has the formula (1) or its acceptable Salt comestiblemente; where an aryl or heteroaryl Ring consists of 5 or 6 members; M is 0, 1, 2, 3 or 4; each ru00b9 is independently selected from alkyl, alkoxy, alkoxy - to Lquilo, hidroxialquilo, Oh, CN, cou2082h, cou2082ru2076, Cho, coru2076, sru2076, halogen, alquenilo, cycloalkyl,Cicloalquenilo, Heterocyclic and heteroaryl, aryl, alkyl; and ru2076 is cu2081u208bu2086; Ru00b2 comprises a branched alkyl or cycloalkyl, optionally substituted with one to four substituents independently selected from alkyl, alkoxyl alkyl, alkoxy, hidroxialquilo, Oh, nhu2082, NHR u2076, nru2076u2082, CN, cou2082h, cou2082ru2076, Cho, coru2076, sh, sru2076, halogen, alquenilo, cycloalkyl, aryl, cicloalquenilo,And ru2076 is cu2081u208bu2086 and heteroaryl alkyl; and where the amide Compound has a Molecular Weight of 500 grams per mole or less.

机译：本申请涉及以下发现：某些酰胺不是天然来源的，非肽酰胺和酰胺衍生物，例如草酰胺，尿素和丙烯酰胺是有用的改性剂，例如风味或风味，风味或风味增强剂或风味剂和风味剂，更多。 1，权利要求1的方法，其特征在于，它们是特定的美味风味改良剂（味精味精）或甜味，甜味或咸味调味剂，或甜味或味觉，食品，饮料和其他可食用或药用产品或组合物的增强剂。：具有式（1）的酰胺化合物或其可接受的盐可食用化合物;芳基或杂芳基环由5或6个成员组成; M为0、1、2、3或4;每个r 9b独立地选自烷基，烷氧基，烷氧基至Lquilo，hidroxialquilo，Oh，CN，co 2u，co 2208，Cho，cor2076，sr2076，卤素，alquenilo，环烷基，Cicloalquenilo杂环和杂芳基，芳基，烷基;和r u2076是c u2081 u208b u2086; R 1b包含支链烷基或环烷基，其任选地被1-4个独立地选自烷基，烷氧基烷基，烷氧基，hidialialquilo，Oh，nh u2082，NHR u2076，nr u2076 u2082，CN，co u2082h的取代基取代，co，，，，，，，且酰胺化合物的分子量为每摩尔500克或更小。

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公开/公告号AR098722A2

专利类型
公开/公告日2016-06-08

原文格式PDF
申请/专利权人 SENOMYX INC.;
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申请/专利号AR2014P104621
发明设计人
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申请日2014-12-11
分类号C07D207/34;A61K31/357;A61K31/381;A61K31/4025;A61K31/4184;A61K31/42;A61K31/4245;A61K31/443;A61K31/47;A61K31/4965;C07C233/65;C07C233/68;C07C275/30;C07D209/42;C07D213/60;C07D215/48;C07D215/54;C07D217/26;C07D231/14;C07D235/04;C07D241/24;C07D261/18;C07D263/54;C07D263/58;C07D271/06;C07D277/56;C07D307/86;C07D317/68;C07D319/16;C07D321/10;C07D333/38;C07D333/60;C07D405/12;C07D409/04;
国家 AR
入库时间 2022-08-21 14:27:37

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