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Method to induce and expand therapeutic alloantigen-specific human regulatory T cells in large-scale
Method to induce and expand therapeutic alloantigen-specific human regulatory T cells in large-scale
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机译:大规模诱导和扩增治疗性同种抗原特异性人类调节性T细胞的方法
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摘要
Methods for inducing, expanding, and/or generating alloantigen-specific regulatory T cells. Alloantigen-specific regulatory T cells can be induced, expanded, and/or generated from naive CD4+CD25− T cells by using CD40-activated B cells. The regulatory T cells can be human T cells. In one embodiment, the alloantigen-specific human regulatory T cells can be CD4highCD25+Foxp3+ regulatory T cells.
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