首页> 外国专利> METHOD FOR DEVELOPMENT OF A PEPTIDE BUILDING BLOCK USEFUL FOR DE NOVO PROTEIN DESIGN

METHOD FOR DEVELOPMENT OF A PEPTIDE BUILDING BLOCK USEFUL FOR DE NOVO PROTEIN DESIGN

机译：用于从头蛋白质设计的肽构建模块的开发方法

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摘要

The present invention relates to a top-down symmetric deconstruction approach which provides a novel alternative means to successfully identify a useful polypeptide “building block” for subsequent “bottom-up” de novo design of target protein architecture. The present invention also pertains to a novel peptides isolated by top-down symmetric deconstruction which may be useful for design or directed evolution of novel proteins with novel functionalities.

机译：本发明涉及一种自上而下的对称解构方法，该方法提供了一种新颖的替代方法来成功地鉴定有用的多肽“构件”，用于随后的靶蛋白结构的“自上而下”的从头设计。本发明还涉及通过自上而下的对称解构分离的新型肽，其可用于设计或定向进化具有新型功能的新型蛋白质。

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公开/公告号US2015361149A1

专利类型
公开/公告日2015-12-17

原文格式PDF
申请/专利权人 FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION INC.;
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申请/专利号US201514751207
发明设计人 MICHAEL BLABER;JIHUN LEE;
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申请日2015-06-26
分类号C07K14/50;G06F19/28;G06F19/16;
国家 US
入库时间 2022-08-21 14:36:31

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