首页> 外国专利> Including peptide to enhance the cell permeability of the lipid membrane structure in the cell permeability of the grant and / or lipid membrane structure, as well as the lipid bound to their peptide as a constituent lipid, is or cell permeability having cell permeability enhanced lipid membrane structure

Including peptide to enhance the cell permeability of the lipid membrane structure in the cell permeability of the grant and / or lipid membrane structure, as well as the lipid bound to their peptide as a constituent lipid, is or cell permeability having cell permeability enhanced lipid membrane structure

机译:包括肽以增强脂质膜结构的细胞通透性,在授予细胞膜的通透性和/或脂质膜结构,以及结合到其肽上的脂质作为组成脂质,是具有细胞通透性的或具有细胞通透性的脂质膜结构体

摘要

Provided are peptides imparting cell permeability to a lipid membrane structure and/or enhancing the cell permeability of a lipid membrane structure, and a lipid membrane structure which comprises, as a constituent lipid, a lipid bound to such a peptide and has cell permeability or shows enhanced cell permeability. The amino acid sequences of the peptides imparting cell permeability to a lipid membrane structure and/or enhancing the cell permeability of a lipid membrane structure are represented by: LX 1 X 2 X 1 X 1 X 1 L, LLX 2 X 1 X 1 X 1 L and LX 1 X 2 X 1 X 1 L (wherein L represents a leucine residue; X 1 represents a polar amino acid residue; and X 2 represents a polar, non-charged and branched chain amino acid residue).
机译:本发明提供赋予脂质膜结构以细胞渗透性和/或提高脂质膜结构的细胞渗透性的肽,以及脂质膜结构,该脂质膜结构包含与该肽结合的脂质作为构成脂质,并且具有细胞渗透性或增强细胞通透性。赋予脂质膜结构细胞通透性和/或增强脂质膜结构细胞通透性的肽的氨基酸序列表示为:LX 1 X 2 X 1 X 1 X 1 L,LLX 2 X 1 X 1 X 1 L和LX 1 X 2 X 1 X 1 L(其中L代表亮氨酸残基; X 1代表极性氨基酸残基; X 2代表极性,不带电荷和支链的氨基酸残基)。

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