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Encapsulated dye-coated noble metal nanoparticles with increased surface-enhanced Raman scattering properties as contrast agents
Encapsulated dye-coated noble metal nanoparticles with increased surface-enhanced Raman scattering properties as contrast agents
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机译：具有增强表面增强拉曼散射特性的包封染料涂层贵金属纳米颗粒作为造影剂
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摘要
The present disclosure provides semiconductor-metal composite nanoparticles having optical properties superior to those of pure materials for use as contrast agents. The composite includes noble metal nanoparticles having a layer of linker molecules bound to the surface of the noble metal nanoparticles and a layer of dye molecules bound to the layer of linker molecules. When dye molecules are bound to noble metal nanoparticles, they are selected to form an ordered structure that exhibits a collective absorption band shift compared to individual dye molecules. This structure is a multi-shell structure with properties suitable for biosensing and other detection applications, showing enhanced Raman scattering compared to nanoparticles with dye molecules attached in a non-regular form Is encapsulated in a stabilizing coating layer that forms [Selection] Figure 1C
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