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Compositions and methods for upregulating hippocampal plasticity and hippocampal-dependent learning and memory

机译:上调海马可塑性和海马依赖性学习记忆的组合物和方法

摘要

Methods for improving hippocampal plasticity and hippocampal mediated learning and memory, and / or methods for improving neuronal synaptic maturation, and / or methods for optimizing or improving neuronal synaptic transmission, and / or Or a method for improving intracellular oxygen delivery or utilization and / or a method for improving ATP synthesis to a subject in need thereof (eg, normal subject, neurotrauma (eg, Subjects recovering from accidents or damage to the brain, stroke, hypoxia, drowning, and suffocation), as well as learning disabilities (eg, reading disabilities, computational disabilities, writing disabilities, integrated motor disabilities (sensory integration disorders), etc.) A sufficient amount over a sufficient amount of time (in at least one subject group, selected from but not limited to) Charge-stabilized oxygen-containing nanostructures having an average diameter of less than m (e.g., nanobubbles) comprising administration of an ionic aqueous solution, a method is provided. [Selection] Figure 8B
机译:改善海马可塑性和海马介导的学习和记忆的方法,和/或改善神经元突触成熟的方法,和/或优化或改善神经元突触传递的方法,和/或改善细胞内氧气输送或利用的方法,和/或一种用于改善有此需要的受试者(例如正常受试者,神经创伤(例如,从事故或脑部损伤,中风,缺氧,溺水和窒息中康复的受试者)恢复ATP)以及学习障碍(例如,阅读障碍,计算障碍,写作障碍,综合运动障碍(感觉统合障碍)等。)在足够长的时间内(在至少一个受试者组中,选自但不限于)电荷稳定的氧-包含平均直径小于m的纳米结构(例如,纳米气泡),包括施用离子水溶液,方法提供了d。 [选择]图8B

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