首页> 外国专利> DIALYSIS CELL FOR AN IN-VITRO RELEASE TEST APPARATUS, USE OF THE DIALYSIS CELL AND IN-VITRO RELEASE TEST APPARATUS

DIALYSIS CELL FOR AN IN-VITRO RELEASE TEST APPARATUS, USE OF THE DIALYSIS CELL AND IN-VITRO RELEASE TEST APPARATUS

机译:用于体外释放试验装置的透析细胞,透析细胞和体外释放试验装置的用途

摘要

The invention relates to a dialysis cell for an in-vitro release test apparatus for identifying a release behavior, such as a release rate, a substance of a material composition, such as a medication, said substance being bonded to molecular carriers such as liposomes, micelles or nanoparticles, relative to a substance absorption fluid having a cell interior and a dialysis membrane at least partially bordering the cell interior which retains the bound substance, is permeable for the substance released in the substance absorption fluid and is at least partially permeable for the substance absorption fluid, wherein the dialysis membrane is fastened to a support structure which is designed for permanent assembly of the dialysis cell at an assembly position which is stationary relative to the in-vitro release test apparatus.
机译:本发明涉及一种用于体外释放测试设备的透析池,该透析池用于确定释放行为,例如释放速率,材料组合物的物质例如药物,所述物质结合至分子载体例如脂质体,相对于具有细胞内部和至少部分地邻接细胞内部并保留结合物质的透析膜的物质吸收流体,胶束或纳米颗粒对于释放在物质吸收流体中的物质是可渗透的,并且对于细胞吸收物质至少是部分可渗透的物质吸收流体,其中透析膜固定在支撑结构上,该支撑结构设计用于在相对于体外释放测试设备固定的组装位置永久地组装透析池。

著录项

  • 公开/公告号EP3047267A1

    专利类型

  • 公开/公告日2016-07-27

    原文格式PDF

  • 申请/专利权人 PHARMA TEST APPARATENBAU AG;

    申请/专利号EP20140766913

  • 发明设计人 WACKER MATTHIAS;JANAS CHRISTINE;

    申请日2014-09-17

  • 分类号G01N33/15;B01D61/24;B01D63/06;G01N13;

  • 国家 EP

  • 入库时间 2022-08-21 14:49:52

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