首页> 外国专利> PROMOTER FOR REGENERATION OF TENDON-BONE JUNCTION TISSUE OR LIGAMENT-BONE JUNCTION TISSUE

PROMOTER FOR REGENERATION OF TENDON-BONE JUNCTION TISSUE OR LIGAMENT-BONE JUNCTION TISSUE

机译:筋骨连接组织或韧带-骨连接组织再生的促进剂

摘要

An object of the present invention is to provide a drug for promoting the regeneration of tendon-bone junction tissue or ligament-bone junction tissue. The present invention relates to a promoter for regeneration of tendon-bone junction tissue or ligament-bone junction tissue including the following (1) or (2) as an active ingredient: (1) the following (1-a), (1-b), or (1-c) (1-a) HGF protein, (1-b) a partial peptide of HGF protein, the peptide having an effect of promoting regeneration of tendon-bone junction tissue or ligament-bone junction tissue, (1-c) a salt of (1-a) or (1-b); (2) DNA including the following (2-a), (2-b), or (2-c), (2-a) DNA encoding HGF protein, (2-b) DNA encoding a partial peptide of HGF protein, the peptide having an effect of promoting regeneration of tendon-bone junction tissue or ligament-bone junction tissue, (2-c) DNA encoding a protein or a peptide, the protein or the peptide having an effect of promoting regeneration of tendon-bone junction tissue or ligament-bone junction tissue, and the DNA hybridizing with DNA comprising a base sequence complementary to (2-a) or (2-b) under a stringent condition.
机译:本发明的目的是提供一种促进肌腱-骨连接组织或韧带-骨连接组织再生的药物。本发明涉及用于肌腱-骨连接组织或韧带-骨连接组织的再生的促进剂,其包含以下(1)或(2)作为有效成分:(1)以下(1-a),(1- b)或(1-c)(1-a)HGF蛋白,(1-b)HGF蛋白的部分肽,该肽具有促进肌腱-骨连接组织或韧带-骨连接组织再生的作用,(1-c)(1-a)或(1-b)的盐;(2)DNA,包括以下(2-a),(2-b)或(2-c),(2-a)编码HGF蛋白的DNA,(2-b)编码HGF蛋白的部分肽的DNA,该肽具有促进肌腱-骨连接组织或韧带-骨连接组织再生的作用,(2-c)编码蛋白质或肽的DNA,该蛋白质或肽具有促进肌腱-骨连接组织或韧带-骨连接组织的再生的作用,并且该DNA与包含与( 2-a)或(2-b)在严格条件下。

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