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EARLY DIAGNOSTIC TECHNIQUE FOR PRIMARY OPEN-ANGLE GLAUCOMA

机译:原发性开角型青光眼的早期诊断技术

摘要

FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to ophthalmology, and can be used for the early diagnosis of primary open-angle glaucoma. That is ensured by measuring and assessing an intraocular pressure, examining visual fields and lachrymal fluid, measuring pro-inflammatory and anti-inflammatory cytokines and additionally measuring them in blood serum. If observing an increase of blood serum IF-?/IL-4, IL-1?/IL-10, TNF-?/IL-10 in the patients with suspected glaucoma, cytokine coefficients equal to 3.66±1.77, 1.9±0.47, 1.20±0.32 respectively in the patients suffering the initial stage of open-angle glaucoma, the relations IF-?/IL-4, IF-?/IL-10, IL-1?/IL-10, TNF-?/IL-10, cytokine coefficients equal to 1.85±0.44, 1.48±0.34, 2.85±0.74, 2.42±0.71 respectively, as well as an increase of lachrymal IF-?/IL-4, IF-?/IL-10, IL-1?/IL-10, TNF-?/IL-10 in the patients with suspected glaucoma, cytokine coefficients equal to 1.11±0.19, 1.06±0,09, 3.81±0.63, 4.04±0.36 respectively, and in the patients with the initial stage of open-angle glaucoma, an increase of IF-?/IL-4, IF-?/IL-10, IL-1?/IL10, cytokine coefficients equal to 1.26±0.22, 0.84±0.08, 3.98±0.61 respectively, primary open-angle glaucoma is diagnosed.EFFECT: method enables simplifying the early diagnosis of the disease with high accuracy and information value.4 dwg
机译:领域:药物。物质:发明是指药物,即眼科,可用于原发性开角型青光眼的早期诊断。通过测量和评估眼压,检查视野和泪液,测量促炎和抗炎细胞因子并另外在血清中测量它们,可以确保这一点。如果观察到可疑青光眼患者的血清IF-α/ IL-4,IL-1β/ IL-10,TNF-α/ IL-10升高,则细胞因子系数等于3.66±1.77、1.9±0.47,患有开角型青光眼的患者分别为1.20±0.32,与IF-α/ IL-4,IF-α/ IL-10,IL-1β/ IL-10,TNF-α/ IL-的关系在图10中,细胞因子系数分别等于1.85±0.44、1.48±0.34、2.85±0.74、2.42±0.71,以及泪液IF-α/ IL-4,IF-α/ IL-10,IL-1β增加。 / IL-10,TNF-α/ IL-10在怀疑患有青光眼的患者中,其细胞因子系数分别等于1.11±0.19、1.06±0.09、3.81±0.63、4.04±0.36原发性开角型青光眼,IF-α/ IL-4,IF-α/ IL-10,IL-1β/ IL10升高,细胞因子系数分别等于1.26±0.22、0.84±0.08、3.98±0.61诊断为开角型青光眼。效果:该方法可以简化疾病的早期诊断,并具有较高的准确性和信息价值。4dwg

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