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DISPERSIBLE TABLET OF DIOCTAHEDRAL SMECTITE AND METHOD FOR PRODUCING IT
DISPERSIBLE TABLET OF DIOCTAHEDRAL SMECTITE AND METHOD FOR PRODUCING IT
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摘要
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to medicine and describes a pharmaceutical composition of dioctahedral smectite presented in the form of a dispersible tablet, as well as a method for producing it. The dispersible tablet is formed by pressing the granules containing dioctahedral smectite in an amount of 800 to 1,200 mg, as well as excipients and target additives in an amount of no more than 50% from a tablet weight. The produced tablet is water-dispersible for 3 minutes to form a dispersion consisting of particles of less than 710 mcm in size, as well as possesses high stability and physical integrity, good mechanical properties in a combination with fast dispersion ability in aqueous solutions.EFFECT: specified tablet composition enables providing good stability of the technological process of the dispersible tablet.2 cl, 2 tbl
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