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BORRELIA HYBRID PROTEIN, NUCLEIC ACID CODING THIS PROTEIN, EXPRESSING CARTRIDGE, VECTOR, METHOD AND KIT FOR DIAGNOSING LYME BORRELIOSIS, VACCINE FOR BORRELIOSIS PREVENTION
BORRELIA HYBRID PROTEIN, NUCLEIC ACID CODING THIS PROTEIN, EXPRESSING CARTRIDGE, VECTOR, METHOD AND KIT FOR DIAGNOSING LYME BORRELIOSIS, VACCINE FOR BORRELIOSIS PREVENTION
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机译:鲍氏杂种蛋白,编码该蛋白的核酸,诊断莱姆病的表达载体,载体,方法和试剂盒,预防流感的疫苗
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摘要
FIELD: medicine, pharmaceutics.;SUBSTANCE: presented group of inventions concerns fused proteins, nucleic acids coding these proteins, an expressing cartridge providing nucleic acid expression, a vector comprising this cartridge, a diagnostic technique for in vitro borreliosis, a kit for this diagnostic technique, which use these proteins, as well as a vaccine composition for preventing borreliosis containing these proteins. The characterised fused proteins contain (i) at least one sequence of DbpA protein of the species Borrelia specified in B. afzelii, B. burgdorferi sensu stricto and B. garinii, and (ii) least one sequence of OspC protein of the species Borrelia specified in B. afzelii, B. burgdorferi sensu stricto and B. garinii.;EFFECT: presented group of inventions enables performing more sensitive and specific analyses related to the presence of certain pathogenic species Borrelia.;11 cl, 8 tbl, 7 ex
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