首页> 外国专利> BORRELIA HYBRID PROTEIN, NUCLEIC ACID CODING THIS PROTEIN, EXPRESSING CARTRIDGE, VECTOR, METHOD AND KIT FOR DIAGNOSING LYME BORRELIOSIS, VACCINE FOR BORRELIOSIS PREVENTION

BORRELIA HYBRID PROTEIN, NUCLEIC ACID CODING THIS PROTEIN, EXPRESSING CARTRIDGE, VECTOR, METHOD AND KIT FOR DIAGNOSING LYME BORRELIOSIS, VACCINE FOR BORRELIOSIS PREVENTION

机译:鲍氏杂种蛋白,编码该蛋白的核酸,诊断莱姆病的表达载体,载体,方法和试剂盒,预防流感的疫苗

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: presented group of inventions concerns fused proteins, nucleic acids coding these proteins, an expressing cartridge providing nucleic acid expression, a vector comprising this cartridge, a diagnostic technique for in vitro borreliosis, a kit for this diagnostic technique, which use these proteins, as well as a vaccine composition for preventing borreliosis containing these proteins. The characterised fused proteins contain (i) at least one sequence of DbpA protein of the species Borrelia specified in B. afzelii, B. burgdorferi sensu stricto and B. garinii, and (ii) least one sequence of OspC protein of the species Borrelia specified in B. afzelii, B. burgdorferi sensu stricto and B. garinii.;EFFECT: presented group of inventions enables performing more sensitive and specific analyses related to the presence of certain pathogenic species Borrelia.;11 cl, 8 tbl, 7 ex
机译:领域:提出的一组发明涉及融合蛋白,编码这些蛋白的核酸,提供核酸表达的表达盒,包含该盒的载体,体外疏螺旋体的诊断技术,用于该诊断的试剂盒使用这些蛋白质的技术,以及用于预防含有这些蛋白质的疏螺旋体病的疫苗组合物。表征的融合蛋白包含(i)至少在B. afzelii,B。burgdorferi sensustricto和B. garinii中指定的疏螺旋体的DbpA蛋白序列,和(ii)在指定的疏螺旋体中指定的OspC蛋白序列效果:提出的发明组能够进行与某些病原体疏螺旋体有关的更灵敏和特异的分析。; 11 cl,8 tbl,7 ex;在B. afzelii,B。burgdorferi sensu stricto和B.

著录项

  • 公开/公告号RU2549698C2

    专利类型

  • 公开/公告日2015-04-27

    原文格式PDF

  • 申请/专利权人 BIOMERE;

    申请/专利号RU20120111811

  • 申请日2010-08-26

  • 分类号C07K14/20;C07K19;C12N15/31;C12N15/63;G01N33/53;A61K39/116;

  • 国家 RU

  • 入库时间 2022-08-21 14:56:22

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