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首页> 外国专利> MACROLIDE DERIVATIVE SUBSTITUTED BY S-4 '-POSITION

MACROLIDE DERIVATIVE SUBSTITUTED BY S-4 '-POSITION

机译：用S-4“-位置代替的宏观衍生物

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摘要

1. The compound represented by the following formula (I): wherein, in the formula, Me represents a methyl group, R represents a hydrogen atom, a C1-6 alkyl group (the C1-6 alkyl group may be substituted with one or two substituents selected from a hydroxy group, an alkoxy group, an amino group, an alkyl group and a group represented by by the formula —NRCOR or by the formula —NRSOR, where R and R, which may be the same or different, are a hydrogen atom or a C 1-6 alkyl group, and where R and R, which may be the same or different, are C 1 group) or a C1-6 alkyl group, R4 represents a hydrogen atom, a 4-8 membered saturated heterocyclic group (a saturated heterocyclic group may be substituted with one or two substituents selected from a Saralkyl group and a C1-6 alkyl group), a alkanoyl group (a alkanoyl group may be substituted by an amino group or a C1-6 alkyl group) or a C1-6 alkyl group which may be substituted by 1 to 3 substituents selected from substituent group 1, or R and R may be combined with the nitrogen atom to which they and are connected to form a 4-8 membered saturated nitrogen-containing heterocyclic group (a saturated nitrogen-containing heterocyclic group may be substituted with 1-3 substituents selected from a hydroxy group, an amino group, a C1-6 alkylamino group and a C1-6 alkyl group (a C1-6 alkyl group may be substituted by an amino group or a C1-6 alkyl group)) 1 represents a group consisting of a C1-6 alkylsulfonyl group, a Salkoxy group, a Cycloalkyl group, a hydroxy group, a phenyl group (the phenyl group may be substituted
机译：1.由下式（I）表示的化合物：其中，在式中，Me表示甲基，R表示氢原子，C 1-6烷基（C 1-6烷基可以被一个或多个取代。选自羟基，烷氧基，氨基，烷基和由式-NRCOR或式-NRSOR表示的基团的两个取代基，其中R和R可以相同或不同。氢原子或C 1-6烷基，且R和R可以相同或不同，为C 1基）或C1-6烷基，R4代表氢原子，为4-8元饱和杂环基（饱和杂环基可以被选自Sar烷基和C1-6烷基的一个或两个取代基取代），烷酰基（烷酰基可以被氨基或C1-6烷基取代）可以被选自取代基组1的1-3个取代基取代的C 1-6烷基或R和R可以与它们所连接的氮原子结合形成4-8元饱和的含氮杂环基（饱和的含氮杂环基可以被1-3个选自羟基，氨基的取代基取代） C 1-6烷基氨基和C 1-6烷基（C 1-6烷基可以被氨基或C 1-6烷基取代）1表示由C 1-6烷基磺酰基组成的基团，烷氧基，环烷基，羟基，苯基（苯基可以被取代

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