ASSESSMENT METHOD effects of treatment in patients with type 2 diabetes mellitus

摘要

A method of evaluating effects of treatment in patients with type 2 diabetes, including an assessment of heart rate variability (HRV), which is performed using the frequency-amplitude spectrum of the Fourier analysis: VLF with the oscillation frequency in the range of 0,004-0,08 Hz, an amplitude of 30-150 points , LF - with a frequency of 0,09-0,16 Hz, an amplitude of 15-25 points, HF - 0.17-0.5 Hz of frequency, amplitude 15-35 points, and performed at 5 stages: in the initial resting position, during mental load, in recovery from mental load at hyperventilation on fire rate, during the period of recovery after hyperventilation; determining power of heart rate variability (HRV) in these frequency ranges determined nonlinear parameter - an approximate entropy (ApEn), with normal values of the amplitudes of spectral components, and approximate entropy diagnosed normal energy homeostasis, administered tablet formulation, while reducing the amplitudes of all spectral components of the HRV, depression or HF, or depression LF, ApEn least 180, unresponsiveness to functional tests - power shortages diagnosed state is assigned two or more groups of drugs, wherein the HRV estimation and determination ApEn performed before and 2 weeks after the start of hypoglycemic therapy and / or in the course of glucose-lowering therapy, and 12 days after correction hypoglycemic therapy, wherein the comparing figures subsequent studies with the previous, and absence amplitude increment HRV spectrum components is not less than 50% and ApEn not less than 5% glucose-lowering therapy ineffective and evaluated again

机译：一种评估2型糖尿病患者治疗效果的方法，包括评估心率变异性（HRV），该方法是使用傅立叶分析的频率-振幅频谱进行的：VLF，振荡频率在0,004- 0,08 Hz，振幅30-150点，LF-频率0,09-0,16 Hz，振幅15-25点，HF-频率0.17-0.5 Hz，振幅15-35点，并分5个阶段执行：在初始休息位置，精神负荷期间，在过度换气时从精神负荷中恢复射速，在过度换气后恢复期间;确定在这些频率范围内的心率变异性（HRV）的功率确定非线性参数-近似熵（ApEn），具有频谱分量幅度的正常值，以及近似熵诊断出的正常能量动态平衡，服用片剂，同时降低HRV，抑郁症或HF或抑郁症LF的所有频谱成分的振幅，ApEn至少为180，对功能测试无反应-功率不足诊断状态被指定为两组或更多组药物，其中HRV估算和确定ApEn在之前和开始降血糖治疗后2周和/或降糖治疗过程中，以及校正降血糖治疗后12天，其中与先前的比较研究以及不存在幅度增加的HRV频谱成分的比较数字不少于50 ％和ApEn不少于5％的降糖治疗无效，并再次评估

著录项

公开/公告号RU2013127303A

专利类型
公开/公告日2014-12-20

原文格式PDF
申请/专利权人 ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ ОБРАЗОВАТЕЛЬНОЕ УЧРЕЖДЕНИЕ ДОПОЛНИТЕЛЬНОГО ПРОФЕССИОНАЛЬНОГО ОБРАЗОВАНИЯ НОВОКУЗНЕЦКИЙ ГОСУДАРСТВЕННЫЙ ИНСТИТУТ УСОВЕРШЕНСТВОВАНИЯ ВРАЧЕЙ МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ (RU);ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ ИНСТИТУТ КОМПЛЕКСНЫХ ПРОБЛЕМ ГИГИЕНЫ И ПРОФЕССИОНАЛЬНЫХ ЗАБОЛЕВАНИЙ СИБИРСКОГО ОТДЕЛЕНИЯ РОССИЙСКОЙ АКАДЕМИИ МЕДИЦИНСКИХ НАУК (RU);
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申请/专利号RU20130127303
发明设计人 БРЫЗГАЛИНА СВЕТЛАНА МИХАЙЛОВНА (RU);ФЛЕЙШМАН АРНОЛЬД НАУМОВИЧ (RU);ГЕРУС АННА ЮРЬЕВНА (RU);
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申请日2013-06-14
分类号A61B5/0452;
国家 RU
入库时间 2022-08-21 14:57:15

ASSESSMENT METHOD effects of treatment in patients with type 2 diabetes mellitus

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