首页> 外国专利> MARKER COMPOSITION COMPRISING APOLIPOPROTEIN M FOR DIAGNOSING ALZHEIMER'S DISEASE

MARKER COMPOSITION COMPRISING APOLIPOPROTEIN M FOR DIAGNOSING ALZHEIMER'S DISEASE

机译:包含载脂蛋白M的MARKER组合物,用于诊断老年痴呆症

摘要

The present invention relates to a biomarker composition comprising apolipoprotein M for diagnosing Alzheimers disease, a composition for diagnosing Alzheimers disease which contains a medicine that measures protein expression level of apolipoprotein M or mRNA expression level of gene coding apolipoprotein M, a kit comprising the composition for diagnosing Alzheimers disease, and a method for providing information to diagnose Alzheimers disease by using the composition. The apolipoprotein M of the present invention meaningfully decreases expression in patients of Alzheimers disease compared to normal people, thereby being used for precisely and quickly diagnosing the Alzheimers disease.
机译:本发明涉及一种包含用于诊断阿尔茨海默氏病的载脂蛋白M的生物标志物组合物,一种用于诊断阿尔茨海默氏病的组合物,一种包含测量载脂蛋白M的蛋白质表达水平或编码载脂蛋白M的基因的mRNA表达水平的药物的试剂盒,该试剂盒包含用于诊断阿尔茨海默氏病的方法,以及通过使用该组合物提供信息以诊断阿尔茨海默氏病的方法。与正常人相比,本发明的载脂蛋白M在阿尔茨海默氏病患者中有意义地降低了表达,从而被用于精确且快速地诊断阿尔茨海默氏病。

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