首页> 外国专利> THE METHOD OF OBTAINING THE AQUEOUS SOLUTION OF CHITOSAN, CHITOSAN COMPOSITION, CHITOSAN AEROSOL, THE METHOD OF PRODUCING THE CHITOSAN HYDROGEL MEMBRANE AND THE METHOD OF PRODUCING CHITOSAN-PROTEIN BIOPOLYMER MATERIAL

THE METHOD OF OBTAINING THE AQUEOUS SOLUTION OF CHITOSAN, CHITOSAN COMPOSITION, CHITOSAN AEROSOL, THE METHOD OF PRODUCING THE CHITOSAN HYDROGEL MEMBRANE AND THE METHOD OF PRODUCING CHITOSAN-PROTEIN BIOPOLYMER MATERIAL

机译:获得壳聚糖的水溶液的方法,壳聚糖组合物,壳聚糖气雾剂,壳聚糖水凝胶膜的制备方法以及壳聚糖蛋白生物聚合物材料的制备方法

摘要

The object of the invention is a method of obtaining the aqueous solution of chitosan and its application in the form of chitosan composition and chitosan aerosol, characterised in that the obtained solution of chemically non-modified microcrystalline chitosan, after neutralization and separation from acidic chitosan solution is replenished with water and then mixed, while during the mixing process the solution is saturated with inorganic acidic oxides, preferably carbon dioxide, until obtaining clear chitosan solution and dissolving chitosan. The object of the invention is also a method of producing chitosan hydrogel membrane characterised in that the aqueous solution of chitosan obtained according to the invention is poured to the mould and then conditioned preferably at a room temperature, under atmospheric pressure conditions. The object of the invention is also a method of producing chitosan-protein biopolymer material characterised in that the aqueous solution of chitosan obtained according to the invention, is mixed with modification additives such as cross-linking compounds, plasticisers, biologically active substances, preserving agents, and then mixed with a dispersion of collagen and/or gelatin, formed, incubated and conditioned according to a known method. Such chitosan-protein biopolymer material can be dried under atmospheric pressure conditions or by lyophilisation, and conditioned according to a known method.
机译:本发明的目的是获得壳聚糖水溶液的方法及其以壳聚糖组合物和壳聚糖气溶胶的形式应用,其特征在于,中和并从酸性壳聚糖溶液中分离后,获得的化学未改性的微晶壳聚糖溶液。向水补充水然后混合,而在混合过程中,溶液用无机酸性氧化物,优选二氧化碳饱和,直到获得澄清的壳聚糖溶液并使壳聚糖溶解。本发明的目的还在于一种制备壳聚糖水凝胶膜的方法,其特征在于将根据本发明获得的壳聚糖的水溶液倒入模具中,然后优选在室温下在大气压条件下进行调节。本发明的目的还在于一种制备壳聚糖-蛋白质生物聚合物材料的方法,其特征在于,将根据本发明获得的壳聚糖的水溶液与改性添加剂例如交联化合物,增塑剂,生物活性物质,防腐剂混合。然后,将其与胶原蛋白和/或明胶的分散体混合,根据已知方法形成,孵育和调节。这种壳聚糖-蛋白质生物聚合物材料可以在大气压条件下或通过冻干干燥,并根据已知方法进行调理。

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