首页> 外国专利> MODIFIED GENE OF HUMAN ACTIVATION-INDUCED CYTIDINE DEAMINASE (AID), A METHOD OF MODIFICATION OF HUMAN AID GENE, A COMPOSITION SHOWING AID ACTIVITY, A METHOD OF PREPARATION OF SUCH COMPOSITION IN A BACTERIAL SYSTEM AND USE OF THE COMPOSITION IN THE ANALYSES OF DNA/RNA AMINATION/DEAMINATION AND/OR METHYLATION/DEMETHYLATION

MODIFIED GENE OF HUMAN ACTIVATION-INDUCED CYTIDINE DEAMINASE (AID), A METHOD OF MODIFICATION OF HUMAN AID GENE, A COMPOSITION SHOWING AID ACTIVITY, A METHOD OF PREPARATION OF SUCH COMPOSITION IN A BACTERIAL SYSTEM AND USE OF THE COMPOSITION IN THE ANALYSES OF DNA/RNA AMINATION/DEAMINATION AND/OR METHYLATION/DEMETHYLATION

机译：人激活诱导的胞嘧啶脱氨酶（AID）的修饰基因，人辅助基因的修饰方法，组合物显示活性，在细菌系统中制备这种组合物的方法以及在DNA分析中使用组合物的方法RNA胺化/脱氨和/或甲基化/二甲基化

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摘要

The subject of the invention is a modified gene of human activation-induced cytidine deaminase (AID), a method of modification of human AID gene, a composition showing AID activity, and a method of preparation of such composition. In particular, the invention concerns a modified gene of human AID for the production of an active enzyme in a bacterial system and use of the composition in the analyses of DNA/RNA amination/deamination and/or methylation/demethylatiori.

机译：本发明的主题是人活化诱导的胞苷脱氨酶（AID）的修饰基因，人AID基因的修饰方法，显示AID活性的组合物以及该组合物的制备方法。特别地，本发明涉及用于在细菌系统中产生活性酶的人AID的修饰基因，以及该组合物在DNA / RNA氨基化/脱氨基和/或甲基化/去甲基化比分析中的用途。

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公开/公告号EP2870241A1

专利类型
公开/公告日2015-05-13

原文格式PDF
申请/专利权人 INSTYTUT CHEMII BIOORGANICZNEJ PAN;
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申请/专利号EP20140703938
发明设计人 BUDZKO LUCYNA;JACKOWIAK PAULINA;FIGLEROWICZ MAREK;
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申请日2014-01-14
分类号C12N9/78;C07K16;
国家 EP
入库时间 2022-08-21 15:02:48

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