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METHODS AND COMPOSITIONS FOR PROGNOSTIC RISK ANALYSIS OF CLEAR CELL RENAL CELL CARCINOMA
METHODS AND COMPOSITIONS FOR PROGNOSTIC RISK ANALYSIS OF CLEAR CELL RENAL CELL CARCINOMA
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机译：透明细胞肾细胞癌预后风险分析的方法和成分
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摘要
Provided are methods for distinguishing clear cell type A (ccA) renal cell carcinoma from clear cell type B (ccB) renal cell carcinoma in a subject. In some embodiments, the method include the steps of obtaining a biological sample from a subject that has clear cell renal cell carcinoma (ccRCC); assaying the biological sample to determine an expression level for one or more and optionally all thirty-four of the gene products listed in Table 1 in the biological sample; and comparing the expression level(s) determined to a statistically validated reference. Also provided are methods for generating prognostic signatures for subject with ccRCC, methods for assessing risk of an adverse outcome of a subject with ccRCC, methods for predicting a clinical outcome of a treatment in a subject having ccRCC, and arrays that can be employed in the practice of the presently disclosed methods.
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