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Method for diagnosing acute renal failure or chronic renal failure

机译:诊断急性肾衰竭或慢性肾衰竭的方法

摘要

Use of neutrophil gelatinase-associated lipocalin (NGAL) as a therapeutic and in a method of treating, reducing, or ameliorating an injury selected from an ischemic injury, an ischemic-reperfusion injury, and a toxin-induced injury, to an organ in a patient. The invention includes administering to the patient NGAL in an amount effective to treat, reduce or ameliorate ischemic, ischemic-reperfusion, or toxin-induced injury to the organ, such as the kidney. A siderophore can be co-administered with the NGAL. The invention also relates to administering a sideophore to enhance a response to secretion of NGAL following an ischemic or toxin-induced injury to an organ in a patient.
机译:中性粒细胞明胶酶相关脂钙蛋白(NGAL)在治疗,减轻或改善选自缺血性损伤,缺血性再灌注损伤和毒素诱导的损伤的方法中的用途患者。本发明包括以有效治疗,减轻或改善局部缺血,局部缺血再灌注或毒素诱导的器官(例如肾脏)损伤的量向患者施用NGAL。铁载体可以与NGAL共同使用。本发明还涉及在患者的缺血或毒素诱导的器官损伤后,施用铁载体以增强对NGAL分泌的反应。

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