首页> 外国专利> COMPOSITION COMPRISING TWO OR MORE ISOFORMS OF HEPATOCYTE GROWTH FACTOR FOR USE IN TREATING INCOMPLETE REVASCULARISATION OF THE MYOCARDIUM AFTER CORONARY ARTERY BYPASS GRAFTING

COMPOSITION COMPRISING TWO OR MORE ISOFORMS OF HEPATOCYTE GROWTH FACTOR FOR USE IN TREATING INCOMPLETE REVASCULARISATION OF THE MYOCARDIUM AFTER CORONARY ARTERY BYPASS GRAFTING

机译：包含两种或两种以上同型肝细胞生长因子的组合物，用于通过通气移植治疗冠状动脉移植后心肌的不完全消失

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摘要

The present invention relates to methods for treating or preventing cardiac conditions in a subject comprising administering to the subject two or more isoforms of hepatocyte growth factor (HGF). The present invention further relates to methods for promoting endothelial cell growth in a blood vessel comprising administering to the blood vessel two or more isoforms of hepatocyte growth factor (HGF). In one embodiment the two or more isoforms of HGF are administered as one or more polynucleotides encoding the isoforms.

机译：本发明涉及在受试者中治疗或预防心脏疾病的方法，该方法包括给予受试者两种或更多种肝细胞生长因子（HGF）同工型。本发明进一步涉及促进血管中内皮细胞生长的方法，其包括将两种或更多种肝细胞生长因子（HGF）同工型给予所述血管。在一个实施方案中，HGF的两种或多种同工型作为编码同种型的一种或多种多核苷酸施用。

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公开/公告号EP2252321B1

专利类型
公开/公告日2015-04-29

原文格式PDF
申请/专利权人 VIROMED CO. LTD.;
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申请/专利号EP20090704660
发明设计人 KIM JONG-MOOK;KIM SUJEONG;HAHN WOONG;
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申请日2009-01-28
分类号A61K38/18;A61K31/70;A61P9/10;
国家 EP
入库时间 2022-08-21 15:08:22

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