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Synthesis of hybrid cyclic peptoids through differential cyclization of monomer and screening for autophagy modulation
Synthesis of hybrid cyclic peptoids through differential cyclization of monomer and screening for autophagy modulation
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机译:通过单体的差异环化合成杂化环状类肽并筛选自噬调节剂
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摘要
The present disclosure relates to a process for synthesis of hybrid cyclic compounds from functionalized amines. In particular, the disclosure relates to a process for the synthesis of small and medium sized hybrid cyclic peptoids from functionalized ?N -(2-aminoethyl) glycine methyl ester monomers. The disclosure further relates to six and 12 membered hybrid cyclic compounds and applications of said compounds in modulation of autophagy.
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