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首页> 外国专利> Implantable drug depot useful for reducing, preventing or treating postoperative pain in a patient and methods of treating or preventing postoperative pain in a patient and for producing an implantable drug deposit.

Implantable drug depot useful for reducing, preventing or treating postoperative pain in a patient and methods of treating or preventing postoperative pain in a patient and for producing an implantable drug deposit.

机译：可植入药物仓库可用于减轻，预防或治疗患者术后疼痛，以及用于治疗或预防患者术后疼痛并产生可植入药物沉积物的方法。

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摘要

The present invention is directed to an implantable drug depot useful for reducing, preventing or treating post-operative pain in a patient in need of such treatment, the implantable drug depot comprising a polymer and a therapeutically effective amount of a local anesthetic or pharmaceutically acceptable salt thereof, wherein the drug depot is implantable at a site beneath the skin to reduce, prevent or treat post-operative pain, and the drug depot is capable of releasing (i) a bolus dose of the local anesthetic or pharmaceutically acceptable salt thereof at a site beneath the skin and (ii) a sustained release dose of an effective amount of the local anesthetic or pharmaceutically acceptable salt thereof over a period of at least 4 days.
机译：本发明涉及可用于减轻，预防或治疗需要这种治疗的患者的术后疼痛的可植入药物贮库，该可植入药物贮库包含聚合物和治疗有效量的局部麻醉剂或药学上可接受的盐。药物贮存库，其中该药物贮存库可植入皮肤下的部位以减轻，预防或治疗术后疼痛，并且该药物贮存库能够释放（i）剂量的局部麻醉药或其药学上可接受的盐。 （ii）在至少4天的时间内持续释放剂量的有效量的局部麻醉药或其药学上可接受的盐。

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