首页>
外国专利>
METHOD TO PRODUCE VON WILLEBRAND MATURE FACTOR FROM VON WILLEBRAND FACTOR PROPeptide, USE OF A VON WILLEBRAND MATURE FACTOR, AND METHOD TO TREAT VON WILLEBRAND DISEASE IN
METHOD TO PRODUCE VON WILLEBRAND MATURE FACTOR FROM VON WILLEBRAND FACTOR PROPeptide, USE OF A VON WILLEBRAND MATURE FACTOR, AND METHOD TO TREAT VON WILLEBRAND DISEASE IN
The present invention relates to a method for producing a mature von Willebrand Factor (VWF) from von Willebrand Factor pro-peptide comprising the steps: immobilizing VWF pro-peptide on an ion exchange resin, incubating the immobilized VWF pro-peptide with furin to obtain immobilized mature VWF, and isolating mature VWF from the ion exchange resin by elution.
展开▼