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Dipeptidyl-peptidase-IV inhibitors for treatment of type 2 diabetes complex with hypertension

机译：二肽基肽酶-IV抑制剂用于治疗2型糖尿病合并高血压

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摘要

The invention comprises novel inhibitors of dipeptidyl peptidase IV (DPP-IV) with beta blocker activity, pharmaceutical compositions comprising therapeutically effective amounts of novel inhibitors of DPP-IV, and novel methods of treating medical conditions are provided. The novel inhibitors of DPP-IV described herein are useful in the treatment of neurological disorders, diabetes, inflammatory disorders such as arthritis, obesity, osteoporosis, hypertension, and glaucoma of such other enumerated conditions as can be treated with inhibitors of DPP-IV and beta blockers.

机译：本发明包括具有β阻断剂活性的二肽基肽酶IV的新型抑制剂（DPP-IV），包含治疗有效量的DPP-IV的新型抑制剂的药物组合物，并且提供了治疗医学病症的新方法。本文所述的DPP-IV的新型抑制剂可用于治疗神经疾病，糖尿病，诸如关节炎，肥胖，骨质疏松，高血压和青光眼的炎性疾病，这些疾病可以用DPP-IV和DPP-IV抑制剂治疗Beta拦截器。

著录项

公开/公告号US9115082B2

专利类型
公开/公告日2015-08-25

原文格式PDF
申请/专利权人 CATHERINE YANG;WEIXING LI;
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申请/专利号US201313744795
发明设计人 CATHERINE YANG;WEIXING LI;
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申请日2013-01-18
分类号C07D207/16;A61K31/40;
国家 US
入库时间 2022-08-21 15:21:08

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