首页> 外国专利> Peptide derivatives for treatment, prevention or alleviation of a condition associated with bone loss or low bone density or to inhibit osteoclast differentiation and stimulation

Peptide derivatives for treatment, prevention or alleviation of a condition associated with bone loss or low bone density or to inhibit osteoclast differentiation and stimulation

机译：用于治疗，预防或缓解与骨质流失或骨密度低有关的病症或抑制破骨细胞分化和刺激的肽衍生物

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摘要

Compounds of formula R¹-A-NH—CH(R²)—CO—R³are presented. The compounds can be used to treat or alleviate conditions associated with bone loss or low bone density, or to inhibit osteoclast differentiation and stimulation, bone resorption and/or loosening of a prosthetic device. The compounds can be administered as a pharmaceutical composition or in a prosthetic device.

机译：提出了式R ^{1 -A-NH-CH（R ^{2 ）-CO-R ^{3 的化合物。所述化合物可用于治疗或减轻与骨丢失或骨密度低有关的病症，或抑制破骨细胞的分化和刺激，骨吸收和/或假体装置的松弛。这些化合物可以作为药物组合物或在修复装置中给药。}}}

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公开/公告号US9169289B2

专利类型
公开/公告日2015-10-27

原文格式PDF
申请/专利权人 STRONGBONE AB;
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申请/专利号US201414257255
发明设计人 ANDERS GRUBB;FRANCISZEK KASPRZYKOWSKI;ULF LERNER;BEATA ZOLNOWSKA;REGINA KASPRZYKOWSKA;
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申请日2014-04-21
分类号A61K38;A61P19/08;A61P19/02;A61P19/10;C07K7/06;C07K5/062;C07K5/072;C07K5/107;C07K5/11;C07D207/16;C07K5/06;C07K5/08;C07K5/10;
国家 US
入库时间 2022-08-21 15:21:38

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