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SYSTEM AND METHOD FOR REAL TIME CLINICAL QUESTIONS PRESENTATION AND MANAGEMENT

机译：实时临床问题表达和管理的系统和方法

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摘要

In a clinical decision support method, outputs of computer-implemented analytical modules are computed for a patient. Information is displayed for the patient pertaining to a clinical question comprising outputs computed for the patient of analytical modules associated with the clinical question. The analytical modules may include modules configured to perform in silico genetic/genomic tests using genetic/genome sequencing (whole genome, whole exome, whole transcriptome, targeted gene panels, etc) or microarray data. A clinical question-module matrix (CQ-M matrix) may be generated for the patient associating clinical questions with analytical modules, and the method may further include populating the clinical questions with outputs computed for the patient of the analytical modules associated with the clinical questions by the CQ-M matrix. Such populating advantageously re-uses outputs computed for the patient when an analytical module is associated with two or more different clinical questions by the CQ-M matrix. This system empowers the clinician to focus on the clinical aspects of patient management while allowing the data complexities of patient genomic data interpretation to be handled by the clinical decision support system.
机译：在临床决策支持方法中，为患者计算计算机实现的分析模块的输出。显示与临床问题有关的患者信息，包括为患者计算的与该临床问题相关的分析模块的输出。分析模块可以包括被配置为使用遗传/基因组测序（整个基因组，整个外显子组，整个转录组，靶向的基因组等）或微阵列数据进行计算机遗传/基因组测试的模块。可以为患者生成临床问题模块矩阵（CQ-M矩阵），以将临床问题与分析模块相关联，并且该方法可以进一步包括用为患者计算的与临床问题相关联的分析模块的输出来填充临床问题由CQ-M矩阵决定。当分析模块通过CQ-M矩阵与两个或多个不同的临床问题相关联时，这种填充有利地重新使用为患者计算的输出。该系统使临床医生可以专注于患者管理的临床方面，同时允许临床决策支持系统处理患者基因组数据解释的数据复杂性。

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