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METHODS FOR INCREASING GENETIC GAIN IN A BREEDING POPULATION

机译:增加种群的遗传增益的方法

摘要

Methods for method for increasing genetic gain in a breeding process are provided. The methods can include (a) providing effects with respect to a trait of interest of a plurality of genome-wide markers in a breeding population; (b) selecting from the breeding population a breeding pair, wherein crossing the breeding pair would produce a subsequent progeny population; (c) inferring or determining haplotypes based on genotypes with respect to the plurality of genome-wide markers for the breeding pair; (d) simulating a cross of the breeding pair to produce a subsequent generation, each member of the progeny generation having a simulated genotype; (e) calculating a genetic potential value of the progeny generation; (f) repeating steps (b)-(e) one or more times, wherein in each iteration of step (b) employs a different breeding pair; (g) ranking each simulated cross; and (h) selecting one or more optimal breeding pairs based on the ranking, wherein the optimal breeding pair(s) selected is/are predicted to generate progeny with increased genetic gain. Also provided are methods for choosing breeding pairs predicted to produce progeny having desired phenotypes, methods for increasing the likelihood of producing progeny individual having desired phenotypes, methods for generating progeny individual having desired genotypes and/or phenotypes, progeny produced thereby, and cells, seeds, parts, and tissues cultures thereof.
机译:提供了用于在育种过程中增加遗传增益的方法的方法。所述方法可以包括:(a)针对育种种群中的多个全基因组标记物的目的性状提供作用; (b)从繁殖种群中选择一个繁殖对,其中杂交该繁殖对将产生随后的后代种群; (c)基于基因型针对育种对的多个全基因组标记来推断或确定单倍型; (d)模拟育种对的杂交以产生后代,后代的每个成员具有模拟的基因型; (e)计算后代的遗传潜力值; (f)重复步骤(b)-(e)一次或多次,其中在步骤(b)的每次迭代中采用不同的育种对; (g)对每个模拟十字架进行排名; (h)基于排名选择一个或多个最佳育种对,其中预测所选择的最佳育种对产生具有增加的遗传增益的后代。还提供了用于选择预测产生具有期望表型的后代的育种对的方法,用于增加产生具有期望表型的后代个体的可能性的方法,用于产生具有期望基因型和/或表型的后代个体的方法,由此产生的后代以及细胞,种子,其部位和组织培养物。

著录项

  • 公开/公告号US2015089691A1

    专利类型

  • 公开/公告日2015-03-26

    原文格式PDF

  • 申请/专利权人 SYNGENTA PARTICIPATIONS AG;

    申请/专利号US201414496695

  • 发明设计人 ZHIGANG GUO;VENKATA KRISHNA VENKATA;

    申请日2014-09-25

  • 分类号A01H1/04;

  • 国家 US

  • 入库时间 2022-08-21 15:23:08

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