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METAL-CHELATING COMPOUNDS HAVING AT LEAST ONE POLYAMINO CHAIN

机译:具有至少一种聚酰胺链的金属螯合化合物

摘要

The invention relates to metal-chelating compounds comprising one or more 8-hydroxyquinoline units substituted in position 2 with a nitrogenous group comprising a polyamino chain, wherein the polyamino chain is N-substituted on said nitrogenous group, to the composition containing same, and to the uses thereof in the therapeutic field and in particular in the treatment of diseases associated with an abnormality in the regulation of metal metabolism resulting in a metal overload in human or animal cells.
机译:本发明涉及一种金属螯合化合物,其包含在位置2处被含多氨基链的含氮基团取代的一个或多个8-羟基喹啉单元的金属螯合化合物,其中所述含氮基团在所述含氮基团上被N-取代。其在治疗领域中的用途,特别是在与金属代谢调节异常相关的疾病的治疗中,所述异常导致人或动物细胞中的金属超载。

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