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The substituted 1-alkyl-thin Bruno phosphorus -4 (1H) - one derivatives, their preparation and their therapeutic application
The substituted 1-alkyl-thin Bruno phosphorus -4 (1H) - one derivatives, their preparation and their therapeutic application
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机译:取代的1-烷基稀布鲁诺磷-4(1H)-一种衍生物,其制备及治疗应用
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摘要
The subject of the present invention is compounds corresponding to the formula (I) in which: X represents a divalent (C2-C5)alkylene radical which is unsubstituted or substituted one or more times by an Alk group; R1 represents a phenyl, a naphthyl, a pyridyl, a 1-benzothienyl or a 1,3-benzodioxolyl; R2 represents a hydrogen atom, a halogen atom, an Alk group, an OAlk group or else a group chosen from S-Alk, SO-Alk, SO2-Alk, CON(R4)-Alk, N(R4)SO2-Alk, N(R4)CO-Alk, N(R4)SO2N(Alk)2; R3 represents a hydrogen atom, a halogen atom, an Alk group or an OAlk group; R4 represents a hydrogen atom or a (C1-C4)alkyl; Alk represents an unsubstituted or substituted (C1-C4)alkyl. Preparation process and therapeutic application.
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