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METHOD OF TREATING SEPSIS ACCOMPANYING ABDOMINAL AND RETROPERITONEAL DISEASES

机译:治疗腹部和腹膜疾病伴脓毒症的方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely surgery and intensive care, and may be used in treating the patients with developed sepsis with underlying abdominal and retroperitoneal diseases. For this purpose, the management starts with a session of endotoxin absorption. That is followed by the intravenous administration of a bactericidal antibiotic, e.g. such as β-lactam or fluoroquinolone in the amount of 1.1-1.5 daily dose; then 30-60 minutes later, endotoxin sorption is combined with de-hydration hemofiltration in a dose of 45 ml/kg/h for 6-8 hours. The whole procedure is accompanied by the infusion therapy using active solutions specified in a group of low- and high-molecular hydroxyethyl starch and dextran in the amount of 5-10 ml/kg/h. Before the beginning of endotoxin sorption, as well as one day after the termination of hemofiltration and sorption, the blood endotoxin concentration is controlled. If the recorded endotoxin concentration is decreased at least by 60%, another procedure is performed.;EFFECT: method provides higher survival rate in the patients suffering the above pathology, as well as reduces a risk of septic shock ensured by the pathogenically caused regimen of the combination of various human body effects providing a degree of systemic endotoxemia to be decreased.;2 cl, 2 ex
机译:技术领域本发明涉及医学,即外科和重症监护,并且可以用于治疗患有潜在的腹部和腹膜后疾病的脓毒症患者。为此,管理从吸收内毒素开始。随后静脉内施用杀菌抗生素,例如如β-内酰胺或氟喹诺酮,每日剂量为1.1-1.5;然后30-60分钟后,以45 ml / kg / h的剂量结合内毒素吸附和脱水血液滤过6-8小时。整个过程伴随着输注疗法,使用的是低分子和高分子羟乙基淀粉和右旋糖酐中指定的活性溶液(5-10 ml / kg / h)。在开始内毒素吸附之前以及终止血液过滤和吸附之后的一天,控制血液内毒素浓度。如果记录的内毒素浓度降低了至少60%,则执行另一种方法。效果:该方法可为患有上述病理的患者提供更高的生存率,并降低由致病性方案引起的败血性休克的风险各种人体作用的结合可降低全身性内毒素血症的程度。; 2 cl,2 ex

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