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ANTINEYRODEGENERATIVNAYA SUBSTANCE AND PROCESS FOR ITS PREPARATION

机译:防霉变种的物质及其制备方法

摘要

1. A method of producing a substance having antineyrodegenerativymi properties with respect to strokes, Alzheimer's disease and aging, characterized in that the electrostimulation is carried out head broiler mode 100-120 A 3-4 for 3-4 s, take blood, incubated at 4-8 ° C for 18-24 hours, serum was collected, successively filtering through filters with a pore diameter of 800 nm (substance selection) and 50 nm (removal of toxins), lyophilized, irradiated with a linear electron accelerator mode 10-40 kGy and stored at 4-8 ° C.2. The pharmaceutical composition of the substance having action on the affected antineyrodegenerativnym β-amyloid and L-glutamate neurons animals at concentrations ranging from 50 to 800 ug / ml of the medium obtained according to claim 1 and a pharmacologically acceptable carrier napolnitel.3. The pharmaceutical substance composition with antineyrodegenerativnymi properties against ischemic stroke and aging at concentrations of 100 mg / kg body weight, prepared according to claims 1 and 2, a pharmacologically acceptable carrier and excipient.
机译:1.一种生产对中风,阿尔茨海默氏病和衰老具有抗腺指腺苷脂代谢特性的物质的方法,其特征在于,电刺激在头肉鸡模式100-120A 3-4下进行3-4s,取血,在70℃下温育。在4-8℃下放置18-24小时,收集血清,依次通过孔径为800 nm(物质选择)和50 nm(去除毒素)的过滤器过滤,冻干,并用线性电子加速器模式照射10- 40 kGy并存储在4-8°C.2。 6.对根据权利要求1获得的培养基的浓度为50至800μg/ ml的对受影响的抗β-淀粉样蛋白和L-谷氨酸神经元动物有作用的物质的药物组合物,以及药学上可接受的载体萘酚。 3.根据权利要求1和2所述的药物组合物,其在100mg / kg体重的浓度下具有针对缺血性中风和衰老的抗neyrodegenerativnymi性质的药物组合物,药理学可接受的载体和赋形剂。

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