首页> 外国专利> METHOD FOR PREPARING RECOMBINANT PORCINE EPIDEMIC DIARRHEA VIRUS (PEDV) VACCINE USING PLANT AND THE PEDV VACCINE THEREOF

METHOD FOR PREPARING RECOMBINANT PORCINE EPIDEMIC DIARRHEA VIRUS (PEDV) VACCINE USING PLANT AND THE PEDV VACCINE THEREOF

机译:用植物制备重组猪流行性腹泻病毒(PEDV)疫苗的方法及其PEDV疫苗

摘要

Provided are: sCOE-Co1 gene in which sCOE, a synthetic gene coding the neutralizing epitope of PEDV, and Co1 gene, a M cell-targeted peptide ligand, are fused, a recombinant vector including the sCOE-Co1 fusion gene, a host cell transformed with the recombinant vector, a method for manufacturing the sCOE-Co1 fusion protein from plant by inducing the recombinant vector including the sCOE-Co1 fusion gene into plant cells, the plant producing the sCOE-Co1 fusion protein manufactured by the method and a seed of the plant, a composition for manufacturing the sCOE-Co1 fusion protein of the plant having the sCOE-Co1 fusion gene, and a PEDV vaccine composition containing the protein manufactured by the method or the plant as an active ingredient.
机译:提供:融合了编码PEDV的中和表位的合成基因sCOE和M细胞靶向肽配体的Co1基因的sCOE-Co1基因,包括sCOE-Co1融合基因的重组载体,宿主细胞。通过用重组载体转化的方法,通过将包含sCOE-Co1融合基因的重组载体导入植物细胞,从植物中制备sCOE-Co1融合蛋白的方法,生产该方法制备的sCOE-Co1融合蛋白的植物和种子所述植物的特征在于,用于制造具有所述sCOE-Co1融合基因的所述植物的sCOE-Co1融合蛋白的组合物,以及包含通过所述方法或所述植物制造的蛋白质作为有效成分的PEDV疫苗组合物。

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