首页> 外国专利> Composition for Dual SPECT/MRI contrast and a process for obtaining SPECT/MRI dual image using the same

Composition for Dual SPECT/MRI contrast and a process for obtaining SPECT/MRI dual image using the same

机译:用于双SPECT / MRI对比度的组合物以及使用该组合物获得SPECT / MRI双图像的方法

摘要

PURPOSE: A single photon emission computed tomography/magnetic resonance imaging (SPECT/MRI) dual contrast composition is provided to effectively acquire an MRI image and a SPECT image of cancer tissues and to prevent excessive exposure by radiation through controlling the content of compounds of chemical formulas 1 and 2 and the order of administration. CONSTITUTION: A SPECT/MRI dual contrast composition contains a first agent containing a compound of chemical formula 1 and a second agent containing a compound of chemical formula 2. The first agent and the second agent are separately arranged. The compound of chemical formula 1 has a structure of chemical formula 1a. The compound of chemical formula 2 has a structure of chemical formula 2a. A method for acquiring a SPECT/MRI dual image comprises the steps of: administering the first agent to a subject person and acquiring a SPECT image; and administering the second agent to the subject person and acquiring an MRI image. [Reference numerals] (AA,BB) Ligand
机译:目的:提供一种单光子发射计算机断层扫描/磁共振成像(SPECT / MRI)双重对比组合物,以有效地获取癌症组织的MRI图像和SPECT图像,并通过控制化学化合物的含量来防止辐射过度暴露配方1和2以及给药顺序。构成:SPECT / MRI双对比剂组合物包含含有化学式1的化合物的第一药剂和含有化学式2的化合物的第二药剂。第一药剂和第二药剂分开布置。化学式1的化合物具有化学式1a的结构。化学式2的化合物具有化学式2a的结构。一种用于获取SPECT / MRI双重图像的方法,包括以下步骤:将第一药剂施用于受试者并获取SPECT图像;以及将第二药剂给予对象人并获取MRI图像。 [参考数字](AA,BB)配体

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