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METHOD FOR SCREENING HEPATOTOXICITY OF DRUG METABOLITE USING HUMAN LIVER MICROSOME
METHOD FOR SCREENING HEPATOTOXICITY OF DRUG METABOLITE USING HUMAN LIVER MICROSOME
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机译:人肝微粒体筛查药物代谢物肝毒性的方法
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摘要
The present invention relates to a method for screening hepatotoxicity of a drug metabolite using human liver microsome (HLM), comprising steps of: 1) culturing hepatocarcinoma cells and treating hepatocarcinoma cells with a test material and HLM; 2) exchanging a medium and culturing the hepatocarcinoma cells; and confirming cytotoxicity in the hepatocarcinoma cells.;COPYRIGHT KIPO 2014;[Reference numerals] (AA) Cell survival rate (the rate compared to a control group)
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