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Detection of Androgen Receptor (AR) mutations in circulating tumor DNA from plasma samples of castration-resistant prostate cancer patients using locked nucleic acid-clamp PCR

机译:使用锁定核酸钳PCR检测去势抵抗性前列腺癌患者血浆样本中循环肿瘤DNA中的雄激素受体(AR)突变

摘要

The present invention is directed to a PCR method, novel LNA-blockers and a kit thereof for the detection of nucleic acid mutation(s) in free circulating DNA as present in plasma.
机译:本发明涉及用于检测血浆中存在的游离循环DNA中的核酸突变的PCR方法,新型LNA阻断剂及其试剂盒。

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