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ACTIVATION OF HUMAN T-HELPER/INDUCER CELL, T-CYTOTOXIC/SUPPRESSOR CELL, B-CELL, AND NATURAL KILLER (NK)-CELLS AND INDUCTION OF NATURAL KILLER CELL ACTIVITY AGAINST K562 CHRONIC MYELOID LEUKEMIA CELLS WITH MODIFIED CITRUS PECTIN
ACTIVATION OF HUMAN T-HELPER/INDUCER CELL, T-CYTOTOXIC/SUPPRESSOR CELL, B-CELL, AND NATURAL KILLER (NK)-CELLS AND INDUCTION OF NATURAL KILLER CELL ACTIVITY AGAINST K562 CHRONIC MYELOID LEUKEMIA CELLS WITH MODIFIED CITRUS PECTIN
Administration of low molecular weight (10,000-20,000 Daltons, or lower) pectins, particularly modified citrus pectins (MCP), like PectaSol-C reduces galectins-3 levels in vivo. Reduction of galectin-3 levels by MCP inhibits inflammation, inhibits fibrosis formation in organs and tissues, and inhibits cancer formation, progression, transformation and metastases. The reduction in circulating, serum and cellular galectin-3, inherently resulting from the administration of MCP, provides benefit over a spectrum of biological conditions, as evidenced by in vivo trials.
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