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Combined therapy for the prevention or treatment of Alzheimer's disease and corresponding kit

机译:预防或治疗阿尔茨海默氏病的联合疗法和相应的试剂盒

摘要

Kit for prevention or treatment of Alzheimer's disease comprises means (M1) for inducing sequestration of amyloid beta in plasma, and apheresis apparatus (A1), containing a solid carrier contactable with blood or plasma fluid, which exhibits an amyloid beta precursor protein (APP) receptor (I). Independent claims are also included for the following: (1) method for the prevention or treatment of Alzheimer's disease comprising administering (M1) and treating the patient with (A1) where APP is removed from the patient's blood by (A1); and (2) use of an amyloid beta mimotope for inclusion in combination therapy comprising (M1) and (A1) for prevention or treatment of Alzheimer's disease. ACTIVITY : Neuroprotective: Nootropic. MECHANISM OF ACTION : None given.
机译:预防或治疗阿尔茨海默氏病的试剂盒包括:诱导血浆中淀粉样蛋白β螯合的装置(M1)和血液分离术器械(A1),其中包含可与血液或血浆液接触的固体载体,该载体表现出淀粉样β蛋白前体蛋白(APP)受体(I)。还包括以下方面的独立权利要求:(1)预防或治疗阿尔茨海默氏病的方法,包括给予(M1)并用(A1)治疗患者,其中通过(A1)从患者血液中去除APP; (2)淀粉样β模拟表位在包含(M1)和(A1)的联合疗法中用于预防或治疗阿尔茨海默氏病的用途。活动:神经保护:促智。作用机理:未给出。

著录项

  • 公开/公告号ES2414872T8

    专利类型

  • 公开/公告日2014-11-06

    原文格式PDF

  • 申请/专利权人 AFFIRIS AG;

    申请/专利号ES20050767978T

  • 发明设计人 MATTNER FRANK;SCHMIDT WALTER;

    申请日2005-07-06

  • 分类号A61P25/28;A61K38/08;A61K39;A61M1/34;

  • 国家 ES

  • 入库时间 2022-08-21 15:55:19

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