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EFAVIRENZ IN-PROCESS IMPURITY IN PRESENCE OF TETRAHYDROFURAN AS SOLVENT.
EFAVIRENZ IN-PROCESS IMPURITY IN PRESENCE OF TETRAHYDROFURAN AS SOLVENT.
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机译:在存在四氢呋喃作为溶剂的情况下,依法韦仑在工艺中的杂质。
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摘要
In one of the aspect of the invention it is provided that a method for synthesis of organic solvent impurity present in the Efavirenz is isolated, the organic solvents associated impurity is due to the solvents present are ethers, nitriles, and ketones further the organic solvent is selected from acetone, propionitrile, acetonitrile; tetrahydrofuran and 1, 2-dimethoxy ethane, more particularly it is tetrahydrofuran, further the structure of the impurity is determined by analytical techniques
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