首页> 外国专利> 2. Compounds from 7-(isobutene-amine)-6,7,8,9-tetrahydropyridine 1,2-a of Indian acrylic acid, regulator of prostaglandin D2 receptor; drug synthesis; for the prevention and treatment of allergic and immunological diseases, such as asthma.

2. Compounds from 7-(isobutene-amine)-6,7,8,9-tetrahydropyridine 1,2-a of Indian acrylic acid, regulator of prostaglandin D2 receptor; drug synthesis; for the prevention and treatment of allergic and immunological diseases, such as asthma.

机译：2.来自印度丙烯酸的7-（异丁烯-胺）-6,7,8,9-四氢吡啶[1,2-a]的化合物，前列腺素D2受体的调节剂;药物合成用于预防和治疗过敏性和免疫性疾病，例如哮喘。

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摘要

The present invention relates to 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives of the formula (I), wherein R1, R2, R3 and R4 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.

机译：本发明涉及式（I）的7-（杂芳基-氨基）-6,7,8,9-四氢吡啶并[1,2-a]吲哚乙酸衍生物，其中R1，R2，R3和R4为说明书中描述的化合物及其在治疗各种前列腺素介导的疾病和病症中用作前列腺素受体调节剂，最特别是用作前列腺素D2受体调节剂，含有这些化合物的药物组合物及其制备方法。

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公开/公告号CL2013002832A1

专利类型
公开/公告日2014-05-23

原文格式PDF
申请/专利权人 IDORSIA PHARMACEUTICALS LTD.;
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申请/专利号CL20130002832
发明设计人 BOSS CHRISTOPH;AISSAOUI HAMED;RICHARD-BILDSTEIN SYLVIA;SIEGRIST ROMAIN;GABILLET JEROME;
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申请日2013-10-01
分类号C07D471/04;A61K31/437;A61P37/08;
国家 CL
入库时间 2022-08-21 15:58:27

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