首页> 外国专利> Compounds Derivatives of 2 - amino - 4 - ariltiazol, TRPA1 Receptor Antagonists, Pharmaceutical composition that comprises; method of treatment of a disease or health condition associated with chronic pain, neuropathic pain, rheumatoid arthritic pain or Pain osteoartritico.

Compounds Derivatives of 2 - amino - 4 - ariltiazol, TRPA1 Receptor Antagonists, Pharmaceutical composition that comprises; method of treatment of a disease or health condition associated with chronic pain, neuropathic pain, rheumatoid arthritic pain or Pain osteoartritico.

机译：2-氨基-4-阿立替唑的化合物衍生物，TRPA1受体拮抗剂，药物组合物，其包含：与慢性疼痛，神经性疼痛，类风湿性关节炎疼痛或骨关节炎疼痛相关的疾病或健康状况的治疗方法。

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摘要

The present invention is related to 2-amino-4-arylthiazole derivatives as TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.

机译：本发明涉及作为TRPA（瞬时受体潜能亚家族A）调节剂的2-氨基-4-芳基噻唑衍生物。特别地，本文所述的化合物可用于治疗或预防由TRPA1（瞬时受体潜在亚家族A，成员1）调节的疾病，状况和/或病症。本文还提供了制备本文所述化合物的方法，其合成中使用的中间体，其药物组合物以及用于治疗或预防由TRPA1调节的疾病，状况和/或病症的方法。

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公开/公告号CL2013001810A1

专利类型
公开/公告日2014-01-24

原文格式PDF
申请/专利权人 GLENMARK PHARMACEUTICALS S.A.;
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申请/专利号CL20130001810
发明设计人 KUMAR SUKEERTHI;THOMAS ABRAHAM;CHAUDHARI SACHIN SUNDARLAL;KANSAGRA BIPIN PARSOTTAM;YEMIREDDY VENKATA RAMANA;KHAIRATKER JOSHI NEELIMA;MUKHOPADHYAY INDRANIL;GUDI GIRISH;
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申请日2013-06-19
分类号C07D491/048;A61K31/427;A61P29/00;C07D513/04;
国家 CL
入库时间 2022-08-21 15:58:29

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