首页> 外国专利> Set of reagents of marking, methods to analyze the presence of one or more polipeptu00cddeos, to select a sample of polipeptu00cddeos, and to determine amounts of polipeptu00cddeos or peptu00cddeos, use of the method, a mixture of polipeptu00cddeos or peptu00cddeos, kit. And, device for marking by multiplexau00c7u00c3o and analysis of samples of protein.

Set of reagents of marking, methods to analyze the presence of one or more polipeptu00cddeos, to select a sample of polipeptu00cddeos, and to determine amounts of polipeptu00cddeos or peptu00cddeos, use of the method, a mixture of polipeptu00cddeos or peptu00cddeos, kit. And, device for marking by multiplexau00c7u00c3o and analysis of samples of protein.

机译：一套标记试剂，分析一个或多个polipept的存在的方法，选择poeptept的样品并确定polipept或pept的量的方法，使用该方法将poeptept的混合物 u00cddeos或pept u00cddeos，套件。并且，用于通过Multiplexa u00c7 u00c3o进行标记和分析蛋白质样品的装置。

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摘要

The present invention describes double labelling reagents with both an isotopic and isobaric label component suitable for differentially labelling different - protein samples. After labelling of the individual protein samples, all samples are pooled. Peptides from the pooled samples are isolated and analysed by mass spectrometry for determining the relative concentration of each differentially double-labelled polypeptide. balance group

机译：本发明描述了具有同位素标记和同量异位标记成分的双标记试剂，其适于差异标记不同的蛋白质样品。标记各个蛋白质样品后，将所有样品合并。分离来自合并样品的肽，并通过质谱分析以测定每种差异双标记多肽的相对浓度。平衡组

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公开/公告号BRPI0718407A2

专利类型
公开/公告日2013-12-17

原文格式PDF
申请/专利权人 KONINKLIJKE PHILIPS ELECTRONICS N. V;
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申请/专利号BR2007PI18407
发明设计人 RALF HOFFMANN;
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申请日2007-10-23
分类号G01N33/68;
国家 BR
入库时间 2022-08-21 15:58:40

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