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Microelectrode array and method for modifying carbon nanotube electrode interface of the same array

机译:微电极阵列及其修饰碳纳米管电极界面的方法

摘要

The present invention discloses a method for modifying a carbon nanotube electrode interface, which modifies carbon nanotubes used as a neuron-electrode interface by performing three stages of modifications and comprises the steps of: carboxylating carbon nanotubes to provide carboxyl functional groups and improve the hydrophilicity of the carbon nanotubes; acyl-chlorinating the carboxylated carbon nanotubes to replace the hydroxyl functional groups of the carboxyl functional groups with chlorine atoms; and aminating the acyl-chlorinated carbon nanotubes to replace the chlorine atoms with a derivative having amine functional groups at the terminal thereof. The modified carbon nanotubes used as the neuron-electrode interface has lower impedance and higher adherence to nerve cells. Thus is improved the quality of neural signal measurement. The present invention also discloses a microelectrode array, wherein the neuron-electrode interface uses carbon nanotubes modified according to the method of the present invention.
机译:本发明公开了一种用于修饰碳纳米管电极界面的方法,其通过执行三个修饰阶段来修饰用作神经元-电极界面的碳纳米管,该方法包括以下步骤:羧化碳纳米管以提供羧基官能团并改善其亲水性。碳纳米管;酰基氯化羧化碳纳米管,用氯原子取代羧基官能团的羟基官能团;胺化酰基氯化碳纳米管,以在其末端具有胺官能团的衍生物取代氯原子。用作神经元-电极界面的改性碳纳米管具有较低的阻抗和对神经细胞的较高粘附性。因此提高了神经信号测量的质量。本发明还公开了一种微电极阵列,其中神经元-电极界面使用根据本发明的方法改性的碳纳米管。

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