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Calcium sulfate composite particles including aggregated calcium sulfate nanoparticles and method of use for bone augmentation
Calcium sulfate composite particles including aggregated calcium sulfate nanoparticles and method of use for bone augmentation
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机译：包括聚集的硫酸钙纳米颗粒的硫酸钙复合颗粒及其用于骨增强的方法
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摘要
Calcium sulfate composite particles for bone augmentation are disclosed. The composite particles are composed of aggregated calcium sulfate nanoparticles of a diameter from about 50 to about 800 nm, which include a mixture of calcium sulfate dihydrate and calcium sulfate hemihydrate. The composite particles have a diameter from about 200 to about 1,200 μm, and a mean half-life no less than 18 days. Further disclosed is a bone grafting material for bone augmentation. The bone grafting material includes a mixture of the calcium sulfate composite particles and a second type of calcium sulfate particles having a particle diameter from about 2 to about 60 μm, at a ratio from 1:1 to 4:1. The method of using the composite particles and the bone grafting material for bone augmentation is also disclosed.
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